血红素化合物的咖啡因衍生物。
Caffeine derivatives of haematin compounds.
作者信息
Gallagher W A, Elliott W B
出版信息
Biochem J. 1967 Nov;105(2):461-5. doi: 10.1042/bj1050461.
Abstract
- Caffeine reacts with haematin to form a caffeine-haematin compound that has a characteristic absorption spectrum. 2. Graphical analysis of the titration of haematin with caffeine shows that 2mol.prop. of caffeine split the dimeric haematin. 3. Thermodynamic parameters suggest that the reaction involves the making and breaking of hydrophobic bonds. 4. Graphical analysis shows dimeric haem to be split by 2mol.prop. of caffeine to yield a compound with an unusual multibanded absorption in the Soret region. 5. It is postulated that the linkage between the haem groups of dimeric haem and the haematin groups of dimeric haematin is essentially hydrophobic in nature.
摘要
- 咖啡因与高铁血红素反应形成具有特征吸收光谱的咖啡因 - 高铁血红素化合物。2. 咖啡因滴定高铁血红素的图形分析表明，2摩尔当量的咖啡因可拆分二聚体高铁血红素。3. 热力学参数表明该反应涉及疏水键的形成和断裂。4. 图形分析表明二聚体血红素被2摩尔当量的咖啡因拆分，产生一种在索雷特区域具有异常多带吸收的化合物。5. 据推测，二聚体血红素的血红素基团与二聚体高铁血红素的高铁血红素基团之间的连接本质上是疏水的。
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