从冰岛青霉中生产橙黄红菌素并分离出一种新的代谢产物，皮巴斯托醇。
Production of luteoskyrin and isolation of a new metabolite, pibasterol, from Penicillium islandicum Sopp.
作者信息
Ghosh A C, Manmade A, Kobbe B, Townsend J M, Demain A L
出版信息
Appl Environ Microbiol. 1978 Mar;35(3):563-6. doi: 10.1128/aem.35.3.563-566.1978.
Abstract
Production of luteoskyrin, a hepatotoxin synthesized by Penicillium islandicum Sopp., was studied with various fermentation methods. Best results were obtained in static fermentations on glutinous rice at 30 degrees C. The isolated yield of pure luteoskyrin was approximately 400 mg per kg of rice. Also produced were skyrin, islandicin, iridoskyrin, rubroskyrin, chrysophanol, mannitol, and erythritol. A new metabolite, which we call pibasterol, was also isolated.
摘要
研究了由冰岛青霉（Penicillium islandicum Sopp.）合成的肝毒素黄天精的生产，采用了各种发酵方法。在30摄氏度下对糯米进行静态发酵获得了最佳结果。每千克大米中纯黄天精的分离产量约为400毫克。还产生了天精、岛青霉素、虹膜黄天精、红天精、大黄酚、甘露醇和赤藓醇。还分离出一种新的代谢产物，我们称之为皮巴斯醇。
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本文引用的文献
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Production of luteoskyrin, a hepatotoxic pigment, by Penicillium islandicum Sopp.冰岛青霉（Penicillium islandicum Sopp）产生肝毒性色素黄绿青霉素。
Appl Microbiol. 1969 Sep;18(3):406-9. doi: 10.1128/am.18.3.406-409.1969.
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