岛青霉产生环氯素和一种新的代谢产物——岛青霉素。
Production of cyclochlorotine and a new metabolite, simatoxin, by Penicillium islandicum Sopp.
作者信息
Ghosh A C, Manmade A, Townsend J M, Bousquet A, Howes J F, Demain A L
出版信息
Appl Environ Microbiol. 1978 Jun;35(6):1074-8. doi: 10.1128/aem.35.6.1074-1078.1978.
Abstract
Production of the hepatotoxin cyclochlorotine by Penicillium islandicum was studied under a variety of fermentation conditions. The best system for production was agitated red wheat. A thin-layer chromatographic method was developed for the detection of this cyclic polypeptide. These experiments have resulted in the isolation of a new toxic metabolite, which we call simatoxin.
摘要
在多种发酵条件下研究了岛青霉产生肝毒素环氯素的情况。最佳生产体系是搅拌的红小麦。开发了一种薄层色谱法用于检测这种环肽。这些实验已分离出一种新的有毒代谢产物，我们称之为西马毒素。
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