传染性单核细胞增多症患者血清的骨髓集落刺激活性
Bone marrow colony-stimulating activity of sera in infectious mononucleosis.
作者信息
Metcalf D, Wahren B
出版信息
Br Med J. 1968 Jul 13;3(5610):99-101. doi: 10.1136/bmj.3.5610.99.
Abstract
From 44 to 100% of sera from patients with infectious mononucleosis exhibited the capacity to stimulate colony formation in vitro by mouse bone marrow cells. The proportion of sera with colony-stimulating activity was highest in patients with a short fever period and developing low Paul-Bunnell titres. Patients with a more severe course of the disease generally displayed no, or only weak, colony-stimulating activity in their sera, and also had higher Paul-Bunnell titres. The level of serum colony-stimulating activity tended to fall in the convalescent stages of the disease.
摘要
传染性单核细胞增多症患者的血清中，有44%至100%表现出在体外刺激小鼠骨髓细胞形成集落的能力。发热期短且嗜异性凝集试验效价低的患者中，具有集落刺激活性的血清比例最高。病情较重的患者，其血清通常没有或仅有微弱的集落刺激活性，且嗜异性凝集试验效价较高。在疾病的恢复期，血清集落刺激活性水平往往会下降。
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