在家采集血样用于糖尿病控制中的血浆葡萄糖检测。
Home blood sampling for plasma glucose assay in control of diabetes.
作者信息
Howe-Davies S, Holman R R, Phillips M, Turner R C
出版信息
Br Med J. 1978 Aug 26;2(6137):596-8. doi: 10.1136/bmj.2.6137.596.
Estimation of plasma glucose in home blood samples is needed to improve diabetic control. Sufficiently precise measurements on capillary blood were obtained by (a) storing Reflotest glucose-oxidase strips in a desiccant container before reading and (b) collecting blood samples into a simple vacuum bottle containing potassium fluoride (assay of sodium content indicating volume of plasma collected). The precision of the methods (+/- 1 SD) was +/-0.35 mmol/1 (+/-6.3 mg/100 ml). Clinical reliability was assessed by measuring the basal plasma glucose concentration at home on different mornings in patients with maturity-onset diabetes, the day-to-day variation (+/- 1 SD) being +/-0.73 and +/-0.92 mmol/1 (+/-13.2 and +/-16.6 mg/100 ml) respectively. The mean basal plasma glucose concentration in all 84 patients with maturity-onset diabetes from three general practices was 8 mmol/1 (144 mg/100 ml), 44 of the values exceeding 6 mmol/1 (108 mg/100 ml). Improving control by monitoring the basal plasma glucose concentration in maturity-onset diabetes might help to prevent diabetic complications.
为改善糖尿病的控制情况，需要对家庭血样中的血糖进行估算。通过以下方法可在毛细血管血样上获得足够精确的测量结果：(a) 在读取结果前，将罗特血糖仪葡萄糖氧化酶试纸条储存在干燥剂容器中；(b) 将血样采集到含有氟化钾的简易真空瓶中（通过测定钠含量来指示采集的血浆量）。这些方法的精密度（±1标准差）为±0.35 mmol/1（±6.3 mg/100 ml）。通过测量成年型糖尿病患者在不同早晨的基础血浆葡萄糖浓度来评估临床可靠性，每日变化（±1标准差）分别为±0.73和±0.92 mmol/1（±13.2和±16.6 mg/100 ml）。来自三个普通诊所的84例成年型糖尿病患者的平均基础血浆葡萄糖浓度为8 mmol/1（144 mg/100 ml），其中44个值超过6 mmol/1（108 mg/100 ml）。通过监测成年型糖尿病患者的基础血浆葡萄糖浓度来改善控制情况，可能有助于预防糖尿病并发症。
Zotero 插件