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A new actinomycin complex produced by a Micromonospora species: fermentation, isolation, and characterization.

作者信息

Wagman G H, Marquez J A, Watkins P D, Gentile F, Murawski A, Patel M, Weinstein M J

出版信息

Antimicrob Agents Chemother. 1976 Mar;9(3):465-9. doi: 10.1128/AAC.9.3.465.

DOI:10.1128/AAC.9.3.465
PMID:56917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC429553/
Abstract

A species of Micromonospora, Micromonospora floridensis NRRL 8020, has been found to produce an actinomycin complex consisting of at least 25 active components. After solvent extraction of the complex, separation of the individual components was carried out by preparative thin-layer chromatography. Hydrolysis and subsequent electrophoretic and chromatographic identification of the amino acid content of each of the isolated components have shown differences from known actinomycins, and the probability exists that these contain a number of amino or imino acids not previously found in other members of this group of antibiotics.

摘要

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本文引用的文献

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Variations on a theme. The actinomycins.主题变奏曲。放线菌素。
Appl Microbiol. 1961 May;9(3):263-7. doi: 10.1128/am.9.3.263-267.1961.

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