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人类滴状母乳的生物学特性。

The biology of human drip breast milk.

作者信息

Lucas A, Gibbs J A, Baum J D

出版信息

Early Hum Dev. 1978 Dec;2(4):351-61. doi: 10.1016/0378-3782(78)90062-2.

DOI:10.1016/0378-3782(78)90062-2
PMID:571325
Abstract

The milk which drips from the opposite breast during breast feeding is used in some centres for feeding premature babies, yet there is little scientific information on the biology of this secretion. Drip breast milk (DBM) differs from expressed breast milk (EBM), both in its contents and in the change in its composition over the period of lactation. The fat concentration and energy value of DBM are low, compared with levels reported for EBM: protein, fat, sodium and energy value in DBM fall with the duration of lactation, whereas magnesium and calcium rise, and lactose, potassium osmolality and lysozyme remain constant. The milk fat content of DBM produced by individual donors is linearly related to the daily volume of DBM produced. Studies on 477 women admitted to the Oxford General Practice Obstetric Unit over 1 yr showed that, of the 75% who were lactating successfully 2 wk after delivery, 19% were producing DBM by 2--4 wk. Women who produced DBM did not differ in age or parity from those lactating women who did not, and their babies did not differ in birthweight, gestation, centile or sex. The suitability of DBM as a food for premature infants is discussed.

摘要

在一些医疗中心,母乳喂养时从另一侧乳房滴出的乳汁被用于喂养早产儿,但关于这种分泌物的生物学特性,科学信息却很少。滴出的母乳(DBM)与挤出的母乳(EBM)在成分以及哺乳期内成分变化方面均有所不同。与已报道的EBM水平相比,DBM的脂肪浓度和能量值较低:DBM中的蛋白质、脂肪、钠和能量值会随着哺乳期的延长而下降,而镁和钙则会上升,乳糖、钾渗透压和溶菌酶保持不变。个体捐赠者产生的DBM中的乳脂肪含量与每日产生的DBM量呈线性相关。对牛津综合实践产科病房1年内收治的477名女性进行的研究表明,在产后2周成功进行母乳喂养的75%的女性中,19%在2至4周时产生了DBM。产生DBM的女性在年龄或胎次上与未产生DBM的哺乳期女性没有差异,她们的婴儿在出生体重、孕周、百分位数或性别方面也没有差异。文中讨论了DBM作为早产儿食物的适用性。

相似文献

1
The biology of human drip breast milk.人类滴状母乳的生物学特性。
Early Hum Dev. 1978 Dec;2(4):351-61. doi: 10.1016/0378-3782(78)90062-2.
2
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Br J Nutr. 2002 Jul;88(1):29-37. doi: 10.1079/BJNBJN2002579.

引用本文的文献

1
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Cochrane Database Syst Rev. 2019 Jul 19;7(7):CD002971. doi: 10.1002/14651858.CD002971.pub5.
2
Formula versus donor breast milk for feeding preterm or low birth weight infants.用于喂养早产儿或低出生体重儿的配方奶与捐赠母乳对比
Cochrane Database Syst Rev. 2018 Jun 20;6(6):CD002971. doi: 10.1002/14651858.CD002971.pub4.
3
A randomised multicentre study of human milk versus formula and later development in preterm infants.
一项关于早产儿母乳与配方奶喂养及其后期发育的随机多中心研究。
Arch Dis Child Fetal Neonatal Ed. 1994 Mar;70(2):F141-6. doi: 10.1136/fn.70.2.f141.
4
Human milk banking: current concepts.
Indian J Pediatr. 1990 May-Jun;57(3):361-74. doi: 10.1007/BF02727916.