Panke E S, Rollag M D, Reiter R J
Endocrinology. 1979 Jan;104(1):194-7. doi: 10.1210/endo-104-1-194.
Pineal melatonin concentrations exhibited a marked diurnal rhythmicity in gold hamsters maintained in a light-dark cycle of 15 h of light and 10 h of darkness. When tissue was collected at 3-h intervals throughout a 24-h period, daytime levels of 95--232 pg/pineal gland rose to concentrations of 760--1335 pg/pineal gland (P greater than 0.001 vs. all other values) at 0400 h, 8 h after the onset of darkness. When tissue was collected sequentially during the dark phase, pineal melatonin concentrations remained significantly elevated from 0200--0500 h (P less than 0.01 and P less than 0.001 vs. daytime values, respectively). Superior cervical ganglionectomy abolished the rhythm of pineal melatonin concentrations, and the concentrations were maintained at 60--105 pg/pineal gland throughout a 24-hr period.
在维持15小时光照和10小时黑暗的明暗循环条件下，金黄仓鼠的松果体褪黑素浓度呈现出明显的昼夜节律。当在24小时内每隔3小时收集一次组织时，白天松果体中95 - 232 pg/松果体的水平在黑暗开始8小时后的0400时升至760 - 1335 pg/松果体的浓度（与所有其他值相比，P>0.001）。当在黑暗阶段依次收集组织时，松果体褪黑素浓度在0200 - 0500时仍显著升高（分别与白天值相比，P<0.01和P<0.001）。双侧颈上神经节切除术消除了松果体褪黑素浓度的节律，并且在整个24小时期间浓度维持在60 - 105 pg/松果体。
