Harrison R M, Taylor D C
Lancet. 1976 May 1;1(7966):948-51. doi: 10.1016/s0140-6736(76)92725-2.
Over 200 children from a group of 628 were followed up after 25 years. The children were identified as having had at least one seizure. Particular attention was given to the long-term prognosis in relation to medical, social, and educational problems. Although nearly two-thirds of the sample suffered minimal ill-effects, the problems of the remainder were considerable. 10-1% had died. Of the survivors 11-2% were confined to institutions, and 6-6% were invalids at home. Just under a quarter had chronic epilepsy. While overall the educational achievement of the sample was good, there was also a considerable number of educational problems. Continuing epilepsy was associated with greatly reduced educational and occupational achievement compared with the group in remission. The study reveals the considerable cost of epilepsy to the community in both human and material terms. It also reveals why epilepsy is regarded as a frightening illness.
在628名儿童中，有200多名儿童在25年后接受了随访。这些儿童被确定至少有过一次癫痫发作。特别关注了与医疗、社会和教育问题相关的长期预后。虽然近三分之二的样本受影响最小，但其余样本的问题相当严重。10.1%的人已经死亡。在幸存者中，11.2%被送进了福利院，6.6%在家中病残。略低于四分之一的人患有慢性癫痫。虽然总体而言样本的教育成绩良好，但也存在相当数量的教育问题。与缓解组相比，持续癫痫与教育和职业成就大幅降低有关。该研究揭示了癫痫在人力和物力方面给社区带来的巨大代价。它还揭示了为什么癫痫被视为一种可怕的疾病。
