缓释氟奋乃静肌肉注射后出现严重的抑郁情绪变化。
Severe depressive mood changes following slow-release intramuscular fluphenazine injection.
作者信息
De Alarcon R, Carney M W
出版信息
Br Med J. 1969 Sep 6;3(5670):564-7. doi: 10.1136/bmj.3.5670.564.
Abstract
Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection. In five cases this depression is thought to have been responsible for suicide. In 8 out of 10 cases the depression responded to electroplexy (E.C.T.). It is recommended that patients who are treated with fluphenazine should be carefully supervised.
摘要
16例最初被诊断为精神分裂症并接受氟奋乃静庚酸酯或癸酸酯治疗的患者在注射后短期内出现了严重抑郁。在5例病例中，这种抑郁被认为是自杀的原因。10例中有8例抑郁对电休克治疗（ECT）有反应。建议对接受氟奋乃静治疗的患者进行仔细监测。
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