多肽（聚α-氨基酸）的抗原性。第十六部分。小鼠体内合成多肽免疫原性的遗传控制。
Antigenicity of polypeptides (poly alpha amino acids). XVI. Genetic control of immunogenicity of synthetic polypeptides in mice.
作者信息
Pinchuck P, Maurer P H
出版信息
J Exp Med. 1965 Oct 1;122(4):673-9. doi: 10.1084/jem.122.4.673.
Abstract
The ability of mice to form antibodies against the random terpolymer glu(57)lys(38)ala(5) is controlled by a codominant Mendelian factor. Three of 7 inbred strains were 100 per cent responders; the others were completely negative. All of these strains could make antibody to related polymers with higher alanine content (10 and 40 mole per cent). Breeding studies using the progeny of Swiss mice indicated that a similar genetic factor was involved.
摘要
小鼠针对随机三聚物glu(57)lys(38)ala(5)形成抗体的能力由一个共显性孟德尔因子控制。7个近交系中有3个是100%反应者；其他的则完全呈阴性。所有这些品系都能对丙氨酸含量更高（10%和40%摩尔）的相关聚合物产生抗体。对瑞士小鼠后代进行的育种研究表明，涉及一个类似的遗传因子。
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J Immunol. 1954 Jan;72(1):52-65.
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