Dahlén G, Berg K
Acta Med Scand. 1976;199(5):413-9. doi: 10.1111/j.0954-6820.1976.tb06757.x.
A series of 30 previously investigated and presumably healthy middle-aged males have been studied, following an oral glucose tolerance test (OGTT). The insulin mean value 120 min after the start of the OGTT was found to be significantly lower in persons possessing the pre-beta1-lipoprotein (pre-beta1 +) and Lp(a) antigen, than in those who were pre-beta1-/Lp(a-). At 60 min during the OGTT, triglyceride and insulin correlated significantly in pre-beta1-/Lp(a-) individuals, but not in pre-beta1 + or Lp (a+) individuals; on the other hand, insulin correlated significantly with blood glucose at this time in the pre-beta1 + and Lp(a+) individuals, but not in the pre-beta1-/Lp(a-). These findings may reflect an important biochemical difference between the two subpopulations.
对30名之前接受过检查且推测健康的中年男性进行了研究，这些男性在口服葡萄糖耐量试验（OGTT）后接受了后续观察。结果发现，在口服葡萄糖耐量试验开始120分钟后，拥有前β1-脂蛋白（前β1 +）和Lp(a)抗原的人的胰岛素平均值显著低于前β1-/Lp(a-)的人。在口服葡萄糖耐量试验的60分钟时，前β1-/Lp(a-)个体的甘油三酯与胰岛素显著相关，而在前β1 +或Lp(a+)个体中则不然；另一方面，此时前β1 +和Lp(a+)个体的胰岛素与血糖显著相关，而在前β1-/Lp(a-)个体中则不然。这些发现可能反映了这两个亚群之间重要的生化差异。
