硫酸奎宁对血液透析患者肌肉痉挛的预防作用
Prevention of muscle cramps in haemodialysis patients by quinine sulphate.
作者信息
Kaji D M, Ackad A, Nottage W G, Stein R M
出版信息
Lancet. 1976 Jul 10;2(7976):66-7. doi: 10.1016/s0140-6736(76)92286-8.
PMID:59150
Abstract
Nine patients on maintenance haemodialysis with frequent muscle cramps were given 320 mg quinine sulphate or placebo (in an identical gelatin capsule) at the beginning of each dialysis for a period of 12 weeks. The frequency of cramps was significantly reduced during dialysis in patients receiving quinine sulphate. None of the haematological, auditory, or visual disturbances ascribed to quinine sulphate were noted.
摘要
9名维持性血液透析且频繁出现肌肉痉挛的患者，在每次透析开始时服用320毫克硫酸奎宁或安慰剂（装在相同的明胶胶囊中），为期12周。接受硫酸奎宁治疗的患者在透析期间痉挛频率显著降低。未观察到任何归因于硫酸奎宁的血液学、听觉或视觉障碍。
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