McCollum J P, Muller D P, Harries J T
Arch Dis Child. 1977 Nov;52(11):887-9. doi: 10.1136/adc.52.11.887.
A test meal for assessing the intraluminal phase of absorption in childhood has been validated. 132 test meals were administered to 110 patients aged 2 weeks to 18 years (mean age 4.3 years). 10 children with suspected malabsorption, who were proven to be normal after extensive investigation, constituted the control group. The activities of pancreatic enzymes, and the total and individual bile salt concentrations are presented for the control subjects, and pancreatic enzyme levels in this group are compared with those seen in children with pancreatic insufficiency (cystic fibrosis). The test meal has been designed so that it can be administered to children with suspected gluten, cows' milk, or disaccharide intolerance. The control data provided a basis for the interpretation of information obtained from the application of such a test meal to the clinical investigation of children with suspected malabsorption.
一种用于评估儿童吸收腔内阶段的试验餐已得到验证。对110名年龄在2周至18岁（平均年龄4.3岁）的患者进行了132次试验餐。10名疑似吸收不良的儿童，经过广泛检查后被证明正常，组成了对照组。给出了对照组受试者的胰腺酶活性、总胆汁盐浓度和个体胆汁盐浓度，并将该组的胰腺酶水平与胰腺功能不全（囊性纤维化）儿童的水平进行了比较。该试验餐的设计使其可用于疑似麸质、牛奶或双糖不耐受的儿童。对照数据为解释将这种试验餐应用于疑似吸收不良儿童临床研究中获得的信息提供了依据。
