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环磷酰胺对中国仓鼠精原细胞着丝粒分离序列的影响。

The effect of cyclophosphamide on the centromere separation sequence in Chinese hamster spermatogonia.

作者信息

Singh J R, Miltenburger H G

出版信息

Hum Genet. 1977 Dec 23;39(3):359-62. doi: 10.1007/BF00295432.

DOI:10.1007/BF00295432
PMID:598845
Abstract

The sequence of centromere separation in spermatogonial chromosomes of untreated and cyclophosphamide-treated Chinese hamsters is described. Centromeres of chromosome 1 and 2 separated much earlier than all other chromosomes, especially 6-8. Cyclophosphamide significantly inhibits the centromere separation in all chromosome groups but does not alter the sequence of separation.

摘要

描述了未处理和经环磷酰胺处理的中国仓鼠精原细胞染色体着丝粒分离的顺序。1号和2号染色体的着丝粒比所有其他染色体,尤其是6 - 8号染色体,分离得早得多。环磷酰胺显著抑制所有染色体组的着丝粒分离,但不改变分离顺序。

相似文献

1
The effect of cyclophosphamide on the centromere separation sequence in Chinese hamster spermatogonia.环磷酰胺对中国仓鼠精原细胞着丝粒分离序列的影响。
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引用本文的文献

1
The effect of cyclophosphamide and isoniazid (INH) alone and in combination on the centromere separation sequence in Chinese hamster bone marrow cells.环磷酰胺和异烟肼单独及联合使用对中国仓鼠骨髓细胞着丝粒分离序列的影响。
Hum Genet. 1980;54(1):93-6. doi: 10.1007/BF00279055.
2
Sequence of centromere separation: analysis of mitotic chromosomes in man.着丝粒分离顺序:人类有丝分裂染色体分析
Hum Genet. 1981;57(3):247-52. doi: 10.1007/BF00278937.
3
Sequence of centromere separation another mechanism for the origin of nondisjunction.着丝粒分离顺序——非整倍体起源的另一种机制。

本文引用的文献

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Cine-micrographic analysis of C-mitosis in endosperm.胚乳中C-有丝分裂的电影显微分析。
Chromosoma. 1958;9(4):332-58. doi: 10.1007/BF02568085.
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环磷酰胺对小鼠骨髓染色体的影响。
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7
Separation of sister centromeres in some chromosomes from cultured human leukocytes. A preliminary survey.来自培养的人白细胞的某些染色体中姐妹着丝粒的分离。初步调查。
J Hered. 1974 May-Jun;65(3):149-52. doi: 10.1093/oxfordjournals.jhered.a108486.
8
Sequence of centromere separation of mitotic chromosomes in Chinese hamster.中国仓鼠有丝分裂染色体着丝粒分离的顺序
Chromosoma. 1976 Mar 31;55(1):75-80. doi: 10.1007/BF00288329.
9
Method for testing mutagenic effects of chemicals on spermatogonia of the Chinese hamster: results obtained with cyclophosphamide, saccharin, and cyclamate.检测化学物质对中国仓鼠精原细胞诱变作用的方法:环磷酰胺、糖精和甜蜜素的实验结果
Arzneimittelforschung. 1975;25(12):1889-96.
10
Cytogenetic effects of cyclophosphamide on mouse spermatogonia.环磷酰胺对小鼠精原细胞的细胞遗传学效应。
Humangenetik. 1975 Sep 10;29(2):135-40. doi: 10.1007/BF00430350.