环磷酰胺对中国仓鼠精原细胞着丝粒分离序列的影响。
The effect of cyclophosphamide on the centromere separation sequence in Chinese hamster spermatogonia.
作者信息
Singh J R, Miltenburger H G
出版信息
Hum Genet. 1977 Dec 23;39(3):359-62. doi: 10.1007/BF00295432.
PMID:598845
Abstract
The sequence of centromere separation in spermatogonial chromosomes of untreated and cyclophosphamide-treated Chinese hamsters is described. Centromeres of chromosome 1 and 2 separated much earlier than all other chromosomes, especially 6-8. Cyclophosphamide significantly inhibits the centromere separation in all chromosome groups but does not alter the sequence of separation.
摘要
描述了未处理和经环磷酰胺处理的中国仓鼠精原细胞染色体着丝粒分离的顺序。1号和2号染色体的着丝粒比所有其他染色体，尤其是6 - 8号染色体，分离得早得多。环磷酰胺显著抑制所有染色体组的着丝粒分离，但不改变分离顺序。
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