Kajiwara T, Tamura K, Suzuki T
Ann Surg. 1977 Dec;186(6):694-9. doi: 10.1097/00000658-197712000-00005.
An experimental study was conducted on the effect of resection of the jejunum and ileum on gastrin release. The intravenous infusion of L. arginine in a dose of 0.5 g per kg body weight for 30 minutes proved to be most practical in evaluating gastrin release in addition to insulin and glucagon release. Serum gastrin levels in response to this dose of arginine were determined before and three weeks, three months and one year after resection of the jejunum and of the ileum. At three weeks, a significant increase in gastrin levels occurred in bothe the fasting state and after stimulation in dogs with either jejunum or ileum resection. At three months, the elevated gastrin response persisted only in those with jejunum resection. By one year, the gastrin levels had fallen in almost all dogs to approximately the preoperative levels.
进行了一项关于空肠和回肠切除对胃泌素释放影响的实验研究。事实证明，以每公斤体重0.5克的剂量静脉输注L-精氨酸30分钟，除了可评估胰岛素和胰高血糖素的释放外，对于评估胃泌素的释放最为实用。在空肠和回肠切除术前以及术后三周、三个月和一年，测定了对该剂量精氨酸反应的血清胃泌素水平。在三周时，空肠或回肠切除的犬在禁食状态和刺激后，胃泌素水平均显著升高。在三个月时，胃泌素反应升高仅持续存在于空肠切除的犬中。到一年时，几乎所有犬的胃泌素水平均降至接近术前水平。
