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影响免疫反应的因素。II. 抗原物理状态及淋巴细胞增殖对兔腹腔注射牛血清白蛋白反应的影响

Factors influencing the immune response. II. Effects of the physical state of the antigen and of lymphoreticular cell proliferation on the response to intraperitoneal injection of bovine serum albumin in rabbits.

作者信息

Pinckard R N, Weir D M, McBride W H

出版信息

Clin Exp Immunol. 1967 May;2(3):343-50.

PMID:6035197
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1578837/
Abstract

The injection of at the same time as centrifuged bovine albumin has been shown not to have the adjuvant effect found when is injected 6 days before. The implication of this is discussed and related to mechanisms of antibody synthesis. Whereas particulate alum-precipitated centrifuged bovine albumin was shown to be more effective than centrifuged bovine albumin in inducing primary antibody stimulation, the reverse was true for secondary stimulation by the intraperitoneal route.

摘要

与离心牛白蛋白同时注射时，已证明其没有在提前6天注射时所发现的佐剂效应。对此的含义进行了讨论，并与抗体合成机制相关联。虽然颗粒状明矾沉淀的离心牛白蛋白在诱导初次抗体刺激方面比离心牛白蛋白更有效，但通过腹腔途径进行二次刺激时情况则相反。

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Factors influencing the immune response. II. Effects of the physical state of the antigen and of lymphoreticular cell proliferation on the response to intraperitoneal injection of bovine serum albumin in rabbits.影响免疫反应的因素。II. 抗原物理状态及淋巴细胞增殖对兔腹腔注射牛血清白蛋白反应的影响
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引用本文的文献

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Factors influencing the immune response. 3. The blocking effect of Corynebacterium parvum upon the induction of acquired immunological unresponsiveness to bovine serum albumin in the adult rabbit.影响免疫反应的因素。3. 短小棒状杆菌对成年兔诱导获得性免疫无反应性以抵抗牛血清白蛋白的阻断作用。
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The effect of preadministration of Corynebacterium parvum on the protection afforded by heat-killed and acetone-killed vaccines against experimental mouse typhoid.短小棒状杆菌预先给药对热灭活和丙酮灭活疫苗针对实验性小鼠伤寒所提供保护作用的影响。
J Hyg (Lond). 1974 Feb;72(1):13-8. doi: 10.1017/s0022172400023147.
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Immunology. 1977 Aug;33(2):253-9.

本文引用的文献

1
Preparation of iodine-131 labelled human growth hormone of high specific activity.高比活度碘-131标记人生长激素的制备
Nature. 1962 May 5;194:495-6. doi: 10.1038/194495a0.
2
VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSE.免疫应答过程中抗体亲和力的变化
Biochemistry. 1964 Jul;3:996-1008. doi: 10.1021/bi00895a027.
3
[ADJUVANT PROPERTIES OF CORYNEBACTERIUM PARVUM ON ANTIBODY PRODUCTION AND ON THE INDUCTION OF DELAYED HYPERSENSITIVITY TOWARD CONJUGATED PROTEINS].短小棒状杆菌对抗体产生及对结合蛋白迟发型超敏反应诱导的佐剂特性
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TOLERANCE TO A PROTEIN ANTIGEN IN ADULT MICE AND THE EFFECT OF NONSPECIFIC FACTORS.成年小鼠对蛋白质抗原的耐受性及非特异性因素的影响
J Immunol. 1963 Dec;91:833-9.
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Immunological unresponsiveness produced in adult guinea pigs by parenteral introduction of minute quantities of hapten or protein antigen.通过肠胃外注射微量半抗原或蛋白质抗原来使成年豚鼠产生免疫无反应性。
Proc Soc Exp Biol Med. 1962 Oct;111:111-5. doi: 10.3181/00379727-111-27717.
6
Specific inhibition of antibody production. II. Paralysis induced in adult mice by small quantities of protein antigen.抗体产生的特异性抑制。II. 少量蛋白质抗原诱导成年小鼠麻痹
Immunology. 1962 May;5(3):378-88.
7
Antibody formation. II. The specific anamnestic antibody response.抗体形成。II. 特异性回忆抗体反应。
J Exp Med. 1961 May 1;113(5):959-70. doi: 10.1084/jem.113.5.959.
8
A quantitative immunochemical measure of the primary interaction between I BSA and antibody.一种对牛血清白蛋白（BSA）与抗体之间主要相互作用的定量免疫化学测定方法。
J Infect Dis. 1958 Nov-Dec;103(3):239-62. doi: 10.1093/infdis/103.3.239.
9
Factors influencing the immune response. I. Effects of the physical state of the antigen and of lymphoreticular cell proliferation on the response to intravenous injection of bovine serum albumin in rabbits.影响免疫反应的因素。I. 抗原物理状态及淋巴细胞增殖对家兔静脉注射牛血清白蛋白反应的影响
Clin Exp Immunol. 1967 May;2(3):331-41.
10
The antibody response: a model based on antagonistic actions of antigen.抗体反应：基于抗原拮抗作用的模型。
J Theor Biol. 1963 Sep;5(2):321-39. doi: 10.1016/0022-5193(63)90067-5.