影响免疫反应的因素。II. 抗原物理状态及淋巴细胞增殖对兔腹腔注射牛血清白蛋白反应的影响
Factors influencing the immune response. II. Effects of the physical state of the antigen and of lymphoreticular cell proliferation on the response to intraperitoneal injection of bovine serum albumin in rabbits.
作者信息
Pinckard R N, Weir D M, McBride W H
出版信息
Clin Exp Immunol. 1967 May;2(3):343-50.
Abstract
The injection of at the same time as centrifuged bovine albumin has been shown not to have the adjuvant effect found when is injected 6 days before. The implication of this is discussed and related to mechanisms of antibody synthesis. Whereas particulate alum-precipitated centrifuged bovine albumin was shown to be more effective than centrifuged bovine albumin in inducing primary antibody stimulation, the reverse was true for secondary stimulation by the intraperitoneal route.
摘要
与离心牛白蛋白同时注射时，已证明其没有在提前6天注射时所发现的佐剂效应。对此的含义进行了讨论，并与抗体合成机制相关联。虽然颗粒状明矾沉淀的离心牛白蛋白在诱导初次抗体刺激方面比离心牛白蛋白更有效，但通过腹腔途径进行二次刺激时情况则相反。
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[ADJUVANT PROPERTIES OF CORYNEBACTERIUM PARVUM ON ANTIBODY PRODUCTION AND ON THE INDUCTION OF DELAYED HYPERSENSITIVITY TOWARD CONJUGATED PROTEINS].短小棒状杆菌对抗体产生及对结合蛋白迟发型超敏反应诱导的佐剂特性
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