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短小棒状杆菌对不同品系小鼠针对绵羊红细胞应答所产生抗体的类别和亚类的影响。

Effect of Corynebacterium parvum on the class and subclass of antibody produced in the response of different strains of mice to sheep erythrocytes.

作者信息

Warr G W, James K

出版信息

Immunology. 1975 Mar;28(3):431-42.

PMID:1092609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1445794/
Abstract

Several strains of mice were injected with sheep erythrocytes (SRBC) using C. parvum as adjuvant. The adjuvant effects on the amounts of class and subclass of antibody produced were ranked in the order IgG2b greater than IgG2a and IgM greater than IgG1. In addition, these effects were shown to vary depending on the time of administration of C. parvum relative to antigen. C parvum was shown to have no adjuvant effect on the response of congenitally athymic mice when given at the same time as the antigen, SRBC. On the basis of the reported observations it is suggested that certain of the adjuvant effects of C. parvum require T-cell function.

摘要

使用微小隐孢子虫作为佐剂，给几株小鼠注射绵羊红细胞（SRBC）。对所产生抗体的类别和亚类数量的佐剂效应按以下顺序排列：IgG2b大于IgG2a，IgM大于IgG1。此外，这些效应显示会因微小隐孢子虫相对于抗原的给药时间而异。当与抗原SRBC同时给药时，微小隐孢子虫对先天性无胸腺小鼠的反应没有佐剂效应。根据所报道的观察结果，提示微小隐孢子虫的某些佐剂效应需要T细胞功能。

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Effect of Corynebacterium parvum on the class and subclass of antibody produced in the response of different strains of mice to sheep erythrocytes.短小棒状杆菌对不同品系小鼠针对绵羊红细胞应答所产生抗体的类别和亚类的影响。
Immunology. 1975 Mar;28(3):431-42.
2
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本文引用的文献

1
[ADJUVANT PROPERTIES OF CORYNEBACTERIUM PARVUM ON ANTIBODY PRODUCTION AND ON THE INDUCTION OF DELAYED HYPERSENSITIVITY TOWARD CONJUGATED PROTEINS].短小棒状杆菌对抗体产生及对结合蛋白迟发型超敏反应诱导的佐剂特性
Ann Inst Pasteur (Paris). 1964 May;106:771-7.
2
Factors influencing the immune response. II. Effects of the physical state of the antigen and of lymphoreticular cell proliferation on the response to intraperitoneal injection of bovine serum albumin in rabbits.影响免疫反应的因素。II. 抗原物理状态及淋巴细胞增殖对兔腹腔注射牛血清白蛋白反应的影响
Clin Exp Immunol. 1967 May;2(3):343-50.
3
Factors influencing the immune response. I. Effects of the physical state of the antigen and of lymphoreticular cell proliferation on the response to intravenous injection of bovine serum albumin in rabbits.影响免疫反应的因素。I. 抗原物理状态及淋巴细胞增殖对家兔静脉注射牛血清白蛋白反应的影响
Clin Exp Immunol. 1967 May;2(3):331-41.
4
Inhibitory effect of injection of Corynebacterium parvum on the growth of tumour transplants in isogenic hosts.短小棒状杆菌注射液对同基因宿主肿瘤移植生长的抑制作用。
Br J Cancer. 1966 Jun;20(2):345-55. doi: 10.1038/bjc.1966.42.
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7Sgamma-1 and 7Sgamma-2 antibody response in the mouse. I. Influence of strain, antigen and adjuvant.小鼠体内7Sγ-1和7Sγ-2抗体反应。I. 品系、抗原和佐剂的影响。
J Immunol. 1966 Apr;96(4):744-53.
6
Further improvements in the plaque technique for detecting single antibody-forming cells.用于检测单个抗体形成细胞的蚀斑技术的进一步改进。
Immunology. 1968 Apr;14(4):599-600.
7
A kinetic study of antibody producing cells in the spleen of mice immunized intravenously with sheep erythrocytes.对静脉注射绵羊红细胞免疫的小鼠脾脏中抗体产生细胞的动力学研究。
Immunology. 1968 Jan;14(1):7-20.
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J Immunol. 1972 Jan;108(1):161-4.
9
Requirement of thymus-dependent lymphocytes for potentiation by adjuvants of antibody formation.胸腺依赖性淋巴细胞对佐剂增强抗体形成的需求。
Nature. 1971 Oct 1;233(5318):330-2. doi: 10.1038/233330a0.
10
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J Exp Med. 1974 May 1;139(5):1215-27. doi: 10.1084/jem.139.5.1215.