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人嗜酸性粒细胞阳离子蛋白的放射免疫测定

Radioimmunoassay of human eosinophil cationic protein.

作者信息

Venge P, Roxin L E, Olsson I

出版信息

Br J Haematol. 1977 Nov;37(3):331-5. doi: 10.1111/j.1365-2141.1977.tb01003.x.

DOI:10.1111/j.1365-2141.1977.tb01003.x
PMID:603764
Abstract

A radioimmunosorbent assay has been developed which allows the detection in serum of a cationic protein derived from eosinophil granulocytes. In 34 healthy individuals the mean level was 31 microgram/1. with a range of 5-55 microgram/l. The serum concentration of 'eosinophil' cationic protein was correlated (p less than 0.001) to the number of eosinophil granulocytes in peripheral blood. Quantitation of 'eosinophil' cationic protein in serum might be useful in the study of eosinophil granulocyte turnover and function in vivo.

摘要

已开发出一种放射免疫吸附测定法,可用于检测血清中源自嗜酸性粒细胞的阳离子蛋白。在34名健康个体中,平均水平为31微克/升,范围为5 - 55微克/升。“嗜酸性粒细胞”阳离子蛋白的血清浓度与外周血中嗜酸性粒细胞的数量相关(p小于0.001)。血清中“嗜酸性粒细胞”阳离子蛋白的定量测定可能有助于研究嗜酸性粒细胞在体内的更新和功能。

相似文献

1
Radioimmunoassay of human eosinophil cationic protein.人嗜酸性粒细胞阳离子蛋白的放射免疫测定
Br J Haematol. 1977 Nov;37(3):331-5. doi: 10.1111/j.1365-2141.1977.tb01003.x.
2
Low levels of eosinophil cationic proteins in patients with asthma.哮喘患者中嗜酸性粒细胞阳离子蛋白水平较低。
Lancet. 1977 Aug 20;2(8034):373-5. doi: 10.1016/s0140-6736(77)90303-8.
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Neutrophil and eosinophil granulocytes in bacterial infection: sequential studies of cellular and serum levels of granule proteins.细菌感染中的中性粒细胞和嗜酸性粒细胞:颗粒蛋白细胞水平和血清水平的序贯研究
Br J Haematol. 1978 Apr;38(4):475-83. doi: 10.1111/j.1365-2141.1978.tb01072.x.
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Blood eosinophils and eosinophil cationic protein after acute myocardial infarction or corticosteroid administration.
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Serum eosinophil cationic protein in active and quiescent ulcerative colitis.活动期和静止期溃疡性结肠炎患者血清嗜酸性粒细胞阳离子蛋白水平
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[Basic research into the measurement of eosinophil cationic protein (ECP) in blood samples].
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Eosinophil granule proteins in peripheral blood granulocytes.外周血粒细胞中的嗜酸性粒细胞颗粒蛋白
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Localization of eosinophil cationic protein, major basic protein, and eosinophil peroxidase in human eosinophils by immunoelectron microscopic technique.应用免疫电子显微镜技术对人嗜酸性粒细胞中的嗜酸性粒细胞阳离子蛋白、主要碱性蛋白和嗜酸性粒细胞过氧化物酶进行定位。
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[Eosinophil cationic protein in patients with bronchial asthma].[支气管哮喘患者中的嗜酸性粒细胞阳离子蛋白]
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