[尼古丁和苯丙胺对体重调节的影响]
[Effect of nicotine and amphetamine on body-weight regulation].
作者信息
Classen W, Bättig K
出版信息
Soz Praventivmed. 1977 Jul-Aug;22(4):197-8. doi: 10.1007/BF02078757.
PMID:605689
Abstract
Twice daily c.c. injections of nicotine or amphetamine, for 6 weeks, produced a stabilization of the body weight at a level below that of the controls. This is attained by a transient hypophagia in normal animals and by a brief hyperphagia in animals emaciated prior to the treatment period. These effects confirm the hypothesis of Powley and Keesey (2) that the set-point for body weight is regulated, and not food intake.
摘要
每天两次皮下注射尼古丁或苯丙胺，持续6周，使体重稳定在低于对照组的水平。正常动物通过短暂的摄食减少，而在治疗期前消瘦的动物则通过短暂的摄食增加来达到这一效果。这些效应证实了波利和基西（2）的假设，即体重的设定点是受调节的，而不是食物摄入量。
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本文引用的文献
1
Weight regulation in normal and hypothalamic hyperphagic rats.正常及下丘脑性食欲亢进大鼠的体重调节
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Relationship of body weight to the lateral hypothalamic feeding syndrome.体重与下丘脑外侧进食综合征的关系。
J Comp Physiol Psychol. 1970 Jan;70(1):25-36. doi: 10.1037/h0028390.
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Nicotine-induced hypophagia and hypodipsia in deprived and in hypothalamically stimulated rats.尼古丁对饥饿及下丘脑受刺激大鼠的摄食及饮水抑制作用
Psychopharmacologia. 1975;41(3):211-7. doi: 10.1007/BF00428926.
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