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[尼古丁和苯丙胺对体重调节的影响]

[Effect of nicotine and amphetamine on body-weight regulation].

作者信息

Classen W, Bättig K

出版信息

Soz Praventivmed. 1977 Jul-Aug;22(4):197-8. doi: 10.1007/BF02078757.

DOI:10.1007/BF02078757
PMID:605689
Abstract

Twice daily c.c. injections of nicotine or amphetamine, for 6 weeks, produced a stabilization of the body weight at a level below that of the controls. This is attained by a transient hypophagia in normal animals and by a brief hyperphagia in animals emaciated prior to the treatment period. These effects confirm the hypothesis of Powley and Keesey (2) that the set-point for body weight is regulated, and not food intake.

摘要

每天两次皮下注射尼古丁或苯丙胺,持续6周,使体重稳定在低于对照组的水平。正常动物通过短暂的摄食减少,而在治疗期前消瘦的动物则通过短暂的摄食增加来达到这一效果。这些效应证实了波利和基西(2)的假设,即体重的设定点是受调节的,而不是食物摄入量。

相似文献

1
[Effect of nicotine and amphetamine on body-weight regulation].[尼古丁和苯丙胺对体重调节的影响]
Soz Praventivmed. 1977 Jul-Aug;22(4):197-8. doi: 10.1007/BF02078757.
2
Effect of nicotine on feeding and body weight in rats: involvement of cocaine- and amphetamine-regulated transcript peptide.尼古丁对大鼠摄食和体重的影响:可卡因和安非他命调节的转录肽的参与。
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Nicotine effects on body weight: a regulatory perspective.尼古丁对体重的影响:监管视角
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Nicotine and amphetamine: differential tolerance and no cross-tolerance for ingestive effects.尼古丁与苯丙胺:对摄食效应的耐受性差异及无交叉耐受性
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Nicotine administration effects on feeding and cocaine-amphetamine-regulated transcript (CART) expression in the hypothalamus.尼古丁给药对下丘脑进食及可卡因-苯丙胺调节转录物(CART)表达的影响。
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[The effect of nicotine on body weight and feeding behavior of rats].[尼古丁对大鼠体重及摄食行为的影响]
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Nicotine lowers the body-weight set-point in male rats.尼古丁会降低雄性大鼠的体重设定点。
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Attentional effects of nicotine and amphetamine in rats at different levels of motivation.尼古丁和苯丙胺对不同动机水平大鼠的注意力影响。
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Variability in development of tolerance to repeated injections of low doses of dl-amphetamine in rats.大鼠对重复注射低剂量dl-苯丙胺耐受性发展的变异性。
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本文引用的文献

1
Weight regulation in normal and hypothalamic hyperphagic rats.正常及下丘脑性食欲亢进大鼠的体重调节
J Comp Physiol Psychol. 1966 Apr;61(2):189-93. doi: 10.1037/h0023126.
2
Relationship of body weight to the lateral hypothalamic feeding syndrome.体重与下丘脑外侧进食综合征的关系。
J Comp Physiol Psychol. 1970 Jan;70(1):25-36. doi: 10.1037/h0028390.
3
Nicotine-induced hypophagia and hypodipsia in deprived and in hypothalamically stimulated rats.尼古丁对饥饿及下丘脑受刺激大鼠的摄食及饮水抑制作用
Psychopharmacologia. 1975;41(3):211-7. doi: 10.1007/BF00428926.