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新泽西州迪克斯堡的甲型猪流感(1976年1月至2月)。二、有病例的单位中的传播与发病率

Swine influenza A at Fort Dix, New Jersey (January-February 1976). II. Transmission and morbidity in units with cases.

作者信息

Gaydos J C, Hodder R A, Top F H, Allen R G, Soden V J, Nowosiwsky T, Russell P K

出版信息

J Infect Dis. 1977 Dec;136 Suppl:S363-8. doi: 10.1093/infdis/136.supplement_3.s363.

DOI:10.1093/infdis/136.supplement_3.s363
PMID:606760
Abstract

Epidemiologic study of 13 influenza A/New Jersey/76 (Hsw1N1) patients indicated that person-to-person transmission had occurred in several distinct military units. Soldiers in eight of these units (companies) were studied to determine whether they had experienced influenza A/New Jersey infections and associated acute respiratory disease. Titers of hemagglutination-inhibiting antibody to influenza A/Mayo Clinic/103/74 (Hsw1n1) antigen were determined. In seven of these eight companies, individuals with titers of greater than or equal to 1:20 were found. In these seven companies, members of platoons with cases (contact platoons) had antibody prevalences of 7%-56%, and members of platoons without cases had prevalences of 0-40%. Hospital admissions for acute respiratory disease were proportionately greater in trainees with A/Mayo Clinic antibody titers of greater than or equal to 1:20 than in trainees without antibody in five of six contact platoons studied.

摘要

对13名甲型流感/新泽西/76(Hsw1N1)患者的流行病学研究表明,人际传播已在几个不同的军事单位中发生。对其中8个单位(连队)的士兵进行了研究,以确定他们是否感染过甲型流感/新泽西病毒并患有相关的急性呼吸道疾病。测定了针对甲型流感/梅奥诊所/103/74(Hsw1n1)抗原的血凝抑制抗体滴度。在这8个连队中的7个连队中,发现抗体滴度大于或等于1:20的个体。在这7个连队中,有病例的排(接触排)成员的抗体阳性率为7%-56%,无病例排的成员阳性率为0-40%。在研究的6个接触排中的5个排中,甲型流感/梅奥诊所抗体滴度大于或等于1:20的受训人员因急性呼吸道疾病入院的比例比没有抗体的受训人员更高。

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