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新泽西州迪克斯堡的甲型猪流感(1976年1月至2月)。III. 疫情传播范围和持续时间。

Swine influenza A at Fort Dix, New Jersey (January-February 1976). III. Extent of spread and duration of the outbreak.

作者信息

Hodder R A, Gaydos J C, Allen R G, Top F H, Nowosiwsky T, Russell P K

出版信息

J Infect Dis. 1977 Dec;136 Suppl:S369-75. doi: 10.1093/infdis/136.supplement_3.s369.

DOI:10.1093/infdis/136.supplement_3.s369
PMID:606761
Abstract

The extent and duration of transmission of influenza A/New Jersey/76 virus at Fort Dix, New Jersey, was examined with use of titers of hemagglutination-inhibiting antibody to influenza A/Mayo Clinic/74 (HswN1) antigen as an index of infection. Five hundred ninety-three soldiers (a 9.3% sample) in basic combat training (BCT) were grouped in weekly cohorts by the date on which BCT was started. Cohorts with 11 of the 12 BCT cases of A/swine influenza began training on January 12, 19, and 26, 1976, respectively; 9%-19% of the trainees in these cohorts had titers of antibody to A/Mayo Clinic antigen of greater than or equal to 1:20. In five other cohorts without cases, which began training before January 12 or after January 26, 0-5% of trainees had titers of greater than or equal to 1:20. Titers observed in persons from military units not in BCT and in the civilian population of the post were not consistent with widespread transmission of the virus. Transmission of influenza A/New Jersey virus at Fort Dix probably occurred between mid-January and mid-February with little involvement of people outside of BCT units.

摘要

以针对甲型流感/梅奥诊所/74(HswN1)抗原的血凝抑制抗体效价作为感染指标,对甲型流感/新泽西/76病毒在新泽西州迪克斯堡的传播范围和持续时间进行了研究。593名接受基础战斗训练(BCT)的士兵(占9.3%的样本)根据开始BCT的日期按周分组。12例甲型猪流感BCT病例中的11例所在队列分别于1976年1月12日、19日和26日开始训练;这些队列中9% - 19% 的受训者针对甲型流感/梅奥诊所抗原的抗体效价大于或等于1:20。在1月12日之前或1月26日之后开始训练的另外五个无病例队列中,0% - 5% 的受训者抗体效价大于或等于1:20。在未参加BCT的军事单位人员以及驻地平民中观察到的抗体效价与该病毒的广泛传播情况不符。甲型流感/新泽西病毒在迪克斯堡的传播可能发生在1月中旬至2月中旬,且很少波及BCT单位以外的人员。

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