Ayer-Le Lievre C, Seiger A
Neurosci Lett. 1984 Oct 12;51(2):287-92. doi: 10.1016/0304-3940(84)90566-4.
Substance P-like immunoreactivity (SPLI) of neuron cell bodies is described here in the parasympathetic ganglia of salivary glands in rat fetuses. When grafted to the anterior eye chamber of adult rats, outgrowth of SPLI fibers was also observed around fetal and postnatal ganglia. These observations are significant for the understanding of salivation mechanisms. They also imply the importance of substance P or related compounds in parasympathetic peripheral neurons. The graft experiments indicate a substantial morphological plasticity of these SPLI neurons on perturbation.
本文描述了大鼠胎儿唾液腺副交感神经节中神经元胞体的P物质样免疫反应性(SPLI)。当移植到成年大鼠眼前房时,在胎儿和出生后神经节周围也观察到SPLI纤维的生长。这些观察结果对于理解唾液分泌机制具有重要意义。它们还暗示了P物质或相关化合物在副交感神经外周神经元中的重要性。移植实验表明这些SPLI神经元在受到干扰时具有显著的形态可塑性。