人类免疫球蛋白基因进化的分子印记：一个新的序列家族。
Molecular footprints of human immunoglobulin gene evolution: a new sequence family.
作者信息
Straubinger B, Pech M, Mühlebach K, Jaenichen H R, Bauer H G, Zachau H G
出版信息
Nucleic Acids Res. 1984 Jul 11;12(13):5265-75. doi: 10.1093/nar/12.13.5265.
Abstract
Analysis of the human VK (ref. 2) gene locus led to the detection of a new sequence family (L sequences). Its copy number is in the range of 10(2). The L sequences, which are about 500 bp long, are found as part of the 3' flanking regions of a clustered set of human VKI genes but they occur also separate from the genes. Models are discussed in which L sequences are viewed as molecular footprints of amplification and transposition processes of VK genes.
摘要
对人类VK（参考文献2）基因座的分析导致发现了一个新的序列家族（L序列）。其拷贝数在10²的范围内。L序列长度约为500 bp，作为一组人VKI基因簇3'侧翼区域的一部分被发现，但它们也独立于这些基因存在。文中讨论了一些模型，其中L序列被视为VK基因扩增和转座过程的分子印记。
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