Staden R
Nucleic Acids Res. 1980 Aug 25;8(16):3673-94. doi: 10.1093/nar/8.16.3673.
This paper describes a new way of storing DNA gel reading data and an accompanying set of computer programs. These programs will perform all the manipulations that are required on data gained by the so-called 'shotgun' method of DNA sequencing. This system simplifies the computer processing involved with this sequencing method and also has the capability of being able at any time during a project to display, lined up in register, all the gel reading covering any section of the sequence.
本文描述了一种存储DNA凝胶读数数据的新方法以及一套配套的计算机程序。这些程序将对通过所谓的DNA测序“鸟枪法”获得的数据进行所有所需的操作。该系统简化了与这种测序方法相关的计算机处理过程,并且能够在项目的任何时候将覆盖序列任何部分的所有凝胶读数对齐显示。