Lee T H, Coligan J E, Sodroski J G, Haseltine W A, Salahuddin S Z, Wong-Staal F, Gallo R C, Essex M
Science. 1984 Oct 5;226(4670):57-61. doi: 10.1126/science.6089350.
Antibodies in sera from patients with adult T-cell leukemia-lymphoma or from healthy carriers of type I human T-cell leukemia virus (HTLV) recognize an antigen of approximately 42 kilodaltons (p42) in cell lines infected with HTLV-I. Radiolabel sequence analysis of cyanogen bromide fragments of p42 led to the conclusion that this antigen is encoded in part by LOR, a conserved portion of the "X" region that is flanked by the envelope gene and the 3' long terminal repeat of HTLV-I. It is possible that this novel product mediates the unique transformation properties of the HTLV family.
来自成人T细胞白血病-淋巴瘤患者或I型人类T细胞白血病病毒（HTLV）健康携带者血清中的抗体，可识别感染HTLV-I的细胞系中一种约42千道尔顿（p42）的抗原。对p42溴化氰片段的放射性标记序列分析得出结论，该抗原部分由LOR编码，LOR是“X”区域的一个保守部分，位于HTLV-I的包膜基因和3'长末端重复序列之间。这种新产物有可能介导HTLV家族独特的转化特性。
