皮质酮长期处理的小鼠棕色脂肪组织线粒体与GDP的结合。
GDP binding to brown-adipose-tissue mitochondria of mice treated chronically with corticosterone.
作者信息
Galpin K S, Henderson R G, James W P, Trayhurn P
出版信息
Biochem J. 1983 Jul 15;214(1):265-8. doi: 10.1042/bj2140265.
Abstract
Cytochrome oxidase activity and mitochondrial GDP binding were decreased in brown adipose tissue of mice treated chronically with corticosterone. These changes occurred both in corticosterone-treated mice fed ad libitum and in treated mice pair-fed to control animals. Although the dietary stimulation of brown-adipose-tissue thermogenesis was suppressed by corticosterone, the acute response to cold was not affected.
摘要
长期用皮质酮处理的小鼠棕色脂肪组织中，细胞色素氧化酶活性和线粒体GDP结合能力降低。这些变化在随意进食的皮质酮处理小鼠以及与对照动物配对喂养的处理小鼠中均有发生。尽管皮质酮抑制了棕色脂肪组织产热的饮食刺激，但对寒冷的急性反应并未受到影响。
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