Zwollo P, Stein G S, Stein J L
Biochem Biophys Res Commun. 1984 Nov 14;124(3):988-93. doi: 10.1016/0006-291x(84)91055-6.
We have isolated from a lambda Ch4A library four human genomic DNA segments containing H1 histone genes. Analysis of the representation and organization of histone coding sequences indicates that three of these cloned DNA segments contain both core and H1 histone genes. One of the cloned human H1 histone genes has no core histone genes in close proximity.
我们从一个λCh4A文库中分离出了四个包含H1组蛋白基因的人类基因组DNA片段。对组蛋白编码序列的呈现和组织方式进行分析表明,这些克隆的DNA片段中有三个同时包含核心组蛋白基因和H1组蛋白基因。其中一个克隆的人类H1组蛋白基因附近没有核心组蛋白基因。