百日咳博德特氏菌对头孢菌素衍生物和亚胺培南的敏感性。
Susceptibility of Bordetella pertussis to cephalosporin derivatives and imipenem.
作者信息
Bannatyne R M, Cheung R
出版信息
Antimicrob Agents Chemother. 1984 Oct;26(4):604-5. doi: 10.1128/AAC.26.4.604.
Abstract
The in vitro activities of 16 cephalosporin derivatives and imipenem against 60 strains of Bordetella pertussis were examined. Cefoperazone, imipenem, and ceftriaxone were the most active, with MICs that inhibited 90% of the strains of 0.006, 0.05, and 0.1 microgram/ml, respectively. Cephalexin, cephradine, and cefsulodin were the least active, with MICs of 25 to 125 micrograms/ml. The remainder of the agents demonstrated intermediate activity.
摘要
检测了16种头孢菌素衍生物和亚胺培南对60株百日咳博德特氏菌的体外活性。头孢哌酮、亚胺培南和头孢曲松活性最强，抑制90%菌株的最低抑菌浓度（MIC）分别为0.006、0.05和0.1微克/毫升。头孢氨苄、头孢拉定和头孢磺啶活性最弱，MIC为25至125微克/毫升。其余药物表现出中等活性。
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