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戊二酸的杀病毒活性对人手指上鼻病毒的灭活作用

Inactivation of rhinovirus on human fingers by virucidal activity of glutaric acid.

作者信息

Hayden G F, Deforest D, Hendley J O, Gwaltney J M

出版信息

Antimicrob Agents Chemother. 1984 Dec;26(6):928-9. doi: 10.1128/AAC.26.6.928.

DOI:10.1128/AAC.26.6.928
PMID:6098223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC180052/
Abstract

Hand lotion containing 2% glutaric acid was significantly more effective than placebo in inactivating rhinovirus serotype 2 on the fingers of human volunteers. It may be possible to develop safe, cosmetically acceptable hand lotions which have durable virucidal activity and can interrupt the hand-to-hand transmission of rhinovirus colds.

摘要

含2%戊二酸的护手霜在使人类志愿者手指上的2型鼻病毒失活方面比安慰剂显著更有效。开发具有持久杀病毒活性且能阻断鼻病毒感冒的手到手传播的安全、美容上可接受的护手霜或许是可行的。

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1
Inactivation of rhinovirus on human fingers by virucidal activity of glutaric acid.戊二酸的杀病毒活性对人手指上鼻病毒的灭活作用
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2
Virucidal activity of glutaric acid and evidence for dual mechanism of action.戊二酸的杀病毒活性及双重作用机制的证据。
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本文引用的文献

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Antiviral activity of an alcoholic hand disinfectant. Comparison of the in vitro suspension test with in vivo experiments on hands, and on individual fingertips.一种酒精类手部消毒剂的抗病毒活性。体外悬液试验与手部及单个指尖体内实验的比较。
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Virucidal activity of glutaric acid and evidence for dual mechanism of action.戊二酸的杀病毒活性及双重作用机制的证据。
Antimicrob Agents Chemother. 1984 Dec;26(6):924-7. doi: 10.1128/AAC.26.6.924.
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Evaluation of virucidal compounds for inactivation of rhinovirus on hands.手部杀灭鼻病毒的杀病毒化合物的评估
Antimicrob Agents Chemother. 1978 Nov;14(5):690-4. doi: 10.1128/AAC.14.5.690.
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Hand-to-hand transmission of rhinovirus colds.鼻病毒感冒的人际传播。
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J Infect Dis. 1976 Jan;133(1):28-36. doi: 10.1093/infdis/133.1.28.
9
An investigation of the possible transmission of Rhinovirus colds through indirect contact.关于鼻病毒感冒通过间接接触可能传播的调查。
J Hyg (Lond). 1975 Oct;75(2):249-58. doi: 10.1017/s0022172400047288.