革兰氏阴性菌中质粒介导的链丝菌素抗性
Plasmid-borne streptothricin resistance in gram-negative bacteria.
作者信息
Tschäpe H, Tietze E, Prager R, Voigt W, Wolter E, Seltmann G
出版信息
Plasmid. 1984 Nov;12(3):189-96. doi: 10.1016/0147-619x(84)90043-x.
PMID:6098905
Abstract
Plasmids, which code for a new type of drug resistance due to the acetylation of streptothricin and belonging to various incompatibility groups (I1, I2, W3, FII, S, X, and N) were identified in gram-negative bacteria. The gene for the acetyltransferase is closely linked to a gene for the streptomycin/spectinomycin adenylyltransferase AAD-3" on a novel type of a transposon, designated Tn1825. This is related to Tn7.
摘要
在革兰氏阴性菌中发现了质粒，这些质粒编码一种新型的耐药性，这种耐药性是由于链丝菌素乙酰化所致，并且属于不同的不相容群（I1、I2、W3、FII、S、X和N）。乙酰转移酶基因与一种新型转座子上的链霉素/壮观霉素腺苷酸转移酶AAD-3"基因紧密相连，该转座子命名为Tn1825。它与Tn7相关。
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