转座子Tn7中三个结构基因盒的位点特异性插入。
Site-specific insertion of three structural gene cassettes in transposon Tn7.
作者信息
Sundström L, Roy P H, Sköld O
机构信息
Department of Pharmaceutical Microbiology, Uppsala University, Sweden.
出版信息
J Bacteriol. 1991 May;173(9):3025-8. doi: 10.1128/jb.173.9.3025-3028.1991.
Abstract
Transposon Tn7 has been known to carry genes for resistance to trimethoprim and spectinomycin. A poorly expressed streptothricin resistance gene, identical to the sat gene found in transposons Tn1825 and Tn1826, was localized between the two mentioned genes in Tn7. The surroundings of all three resistance genes indicated site-specific insertion of genetic cassettes.
摘要
转座子Tn7已知携带对甲氧苄啶和壮观霉素的抗性基因。一个表达不佳的链丝菌素抗性基因，与转座子Tn1825和Tn1826中发现的sat基因相同，位于Tn7中上述两个基因之间。所有三个抗性基因的周边区域表明了遗传盒的位点特异性插入。
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