采用阴离子交换萃取技术的头孢唑肟高效液相色谱分析法
High-pressure liquid chromatographic assay of ceftizoxime with an anion-exchange extraction technique.
作者信息
Fasching C E, Peterson L R, Bettin K M, Gerding D N
出版信息
Antimicrob Agents Chemother. 1982 Aug;22(2):336-7. doi: 10.1128/AAC.22.2.336.
Abstract
An anion-exchange extraction method was used in conjunction with high-pressure liquid chromatography for assay of ceftizoxime in 181 serum samples. Comparison of this method with bioassay gave a linear regression line described by Y = 1.11 + 0.98 X, with a correlation coefficient of 0.984. The anion-exchange extraction method is a fast, reliable method of preparing serum samples containing ceftizoxime for assay by liquid chromatography.
摘要
采用阴离子交换萃取法结合高压液相色谱法对181份血清样本中的头孢唑肟进行检测。将该方法与生物测定法进行比较，得到的线性回归线为Y = 1.11 + 0.98X，相关系数为0.984。阴离子交换萃取法是一种快速、可靠的方法，用于制备含头孢唑肟的血清样本以进行液相色谱检测。
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