Miller G J, Beckles G L, Alexis S D, Byam N T, Price S G
Lancet. 1982 Jul 24;2(8291):200-3. doi: 10.1016/s0140-6736(82)91041-8.
Prevalence of coronary heart disease (CHD) and fasting serum lipoprotein concentrations in ethnic groups in Port of Spain, Trinidad, were compared. In a total community survey of 1416 men aged 35-69 years, angina pectoris, a history of possible myocardial infarction, and major Q waves on the electrocardiogram were significantly more common in men of Indian descent than in other ethnic groups (relative risk about 3/1). Indians had significantly lower high-density-lipoprotein-cholesterol (HDLCh) concentrations and significantly higher low-density-lipoprotein-cholesterol (LDLCh) concentrations than other groups. After allowance for age and ethnic group, men with major Q waves or a history of possible myocardial infarction had a significantly greater ratio of LDLCh/HDLCh that men without either. Comparison of surveys in the Caribbean suggests that in this region CHD is prevalent only in communities in which a sizeable proportion of men have an LDHCh/HDLCh ratio greater than 6 and an LDLCh concentration above 5 mmol/l.
对特立尼达西班牙港不同种族群体的冠心病（CHD）患病率和空腹血清脂蛋白浓度进行了比较。在一项针对1416名年龄在35 - 69岁男性的全社区调查中，心绞痛、可能的心肌梗死病史以及心电图上的主要Q波在印度裔男性中比其他种族群体更为常见（相对风险约为3/1）。印度人的高密度脂蛋白胆固醇（HDLCh）浓度显著低于其他群体，而低密度脂蛋白胆固醇（LDLCh）浓度显著高于其他群体。在考虑年龄和种族因素后，有主要Q波或可能的心肌梗死病史的男性的LDLCh/HDLCh比值显著高于没有这些情况的男性。加勒比地区的调查比较表明，在该地区，冠心病仅在相当比例男性的LDHCh/HDLCh比值大于6且LDLCh浓度高于5 mmol/l的社区中流行。
