Kirpichnikova T P, Kozyrev D P, Mishchenko B S, Rybchin V N
Genetika. 1977;13(1):105-13.
A set of c-mutants of the phage phi80 is isolated. These mutants fit into three genes. According to plaque morphology and frequency of lysogenization of mutants, the genes were named cI, cII and cIII as it was previously done for phage lambda. Their order, determinated by mutant phage crosses, is cIII-sus326-cI-cII-sus250. Sus326 is a mutation in the gene 15, so it is probably an analogue of the N gene of the phage lambda. Thermoinducible mutants of the phage phi80 cts11 and cts12 correspond to the mutant types cItsB and cItsA of the phage lambda and they complement each other. Thus, it is supposed that phi80 phage repressor molecules consist of few protein subunits.
分离出了一组噬菌体φ80的c突变体。这些突变体可归入三个基因。根据突变体的噬菌斑形态和溶原化频率,这些基因被命名为cI、cII和cIII,就像之前对噬菌体λ所做的那样。通过突变噬菌体杂交确定它们的顺序为cIII-sus326-cI-cII-sus250。Sus326是基因15中的一个突变,所以它可能是噬菌体λ的N基因的类似物。噬菌体φ80 cts11和cts12的热诱导突变体分别对应于噬菌体λ的cItsB和cItsA突变类型,并且它们相互互补。因此,推测φ80噬菌体阻遏物分子由少数蛋白质亚基组成。