Kelly N M, Fitzgerald M X, Tempany E, O'Boyle C, Falkiner F R, Keane C T
Lancet. 1982 Sep 25;2(8300):688-90. doi: 10.1016/s0140-6736(82)90714-0.
Over a 12-months period respiratory Pseudomonas aeruginosa isolated from CF patients were typed by serology and pyocin production to determine whether cross-infection was occurring. Results of typing were interpreted in relation to the degree of contact patients had with each other. One strain appeared in 4 unrelated patients. However, since none of these patients had been in contact with each other the strains considered to have been acquired from the environment. Each of six pairs of siblings shared the same strain, but the pairs of strains were distinct from each other. These results suggest that the environment is the most important source of Pseudomonas strains for CF patients and that for cross-infection to occur prolonged intimate contact is required.
在12个月的时间里，对从囊性纤维化（CF）患者中分离出的呼吸道铜绿假单胞菌进行血清学和绿脓菌素产生情况分型，以确定是否发生交叉感染。分型结果根据患者之间的接触程度进行解读。一种菌株出现在4名无亲属关系的患者中。然而，由于这些患者彼此之间没有接触，这些菌株被认为是从环境中获得的。六对兄弟姐妹中的每一对都共享相同的菌株，但这些菌株对彼此不同。这些结果表明，环境是CF患者铜绿假单胞菌菌株的最重要来源，并且要发生交叉感染需要长时间的密切接触。
