Norell S, Ahlbom A, Lipping H, Osterblom L
Lancet. 1983 Feb 26;1(8322):462-3. doi: 10.1016/s0140-6736(83)91453-8.
A tenfold increased risk for oesophageal cancer, more often localised in the upper than in the lower third of the oesophagus, was found in a 13-year follow-up of vulcanisation workers. The risk for laryngeal cancer was also significantly raised. The study was based on a record linkage between the 1960 census and the cancer registry in Sweden. The rise in oesophageal cancer cannot be explained by alcohol consumption or other factors previously known to be associated with this disease.
在对硫化工人进行的13年随访中发现,他们患食管癌的风险增加了10倍,且食管癌更常发生在食管上三分之一而非下三分之一处。患喉癌的风险也显著升高。该研究基于1960年瑞典人口普查记录与癌症登记处之间的记录关联。食管癌发病率的上升无法用饮酒或其他已知与该疾病相关的因素来解释。