Silman A J, Locke C, Mitchell P, Humpherson P
Lancet. 1983 May 28;1(8335):1179-82. doi: 10.1016/s0140-6736(83)92463-7.
28 patients who had a sustained diastolic blood pressure of 95 to 104 mm Hg and who had no treatment for it for at least 13 months before the trial, but who were otherwise unselected, took part in a randomised controlled trial in which the effect of a restricted sodium diet was compared with that of a general health package. The general health package did not include any specific hypotensive procedures. Changes in blood pressure were measured at predetermined intervals over the course of a year. Within each group both systolic and diastolic blood pressure fell to a highly significant extent after a year, but there was no significant difference between the groups. It would thus seem that the antihypertensive effect of a restricted sodium diet may be related to the increased consultation and monitoring activity of such intervention rather than to the dietary manipulation itself.
28名患者,其舒张压持续维持在95至104毫米汞柱之间,在试验前至少13个月未接受过针对此血压情况的治疗,且除此之外未作其他筛选,参与了一项随机对照试验,该试验比较了限钠饮食与一般健康套餐的效果。一般健康套餐不包括任何特定的降压措施。在一年的时间里,按照预定的时间间隔测量血压变化。每组患者的收缩压和舒张压在一年后均显著下降,但两组之间无显著差异。因此,限钠饮食的降压效果可能与这种干预增加的咨询和监测活动有关,而非与饮食调整本身有关。