Grobbee D E, Hofman A
Br Med J (Clin Res Ed). 1986 Jul 5;293(6538):27-9. doi: 10.1136/bmj.293.6538.27.
Data from 13 randomised trials on the effect of sodium restriction on blood pressure were analysed. The hypotensive effect of sodium restriction was found to be small and restricted largely to systolic blood pressure, which fell by an average of 3.6 mm Hg (range 0.5-10.0 mm Hg). The reduction increased with age and in those with higher blood pressure. Sodium restriction therefore seems to be of limited use in those who are most eligible for non-pharmacological treatment of high blood pressure--namely, young patients with mild hypertension.
对13项关于钠限制对血压影响的随机试验数据进行了分析。发现钠限制的降压作用较小,且主要限于收缩压,收缩压平均下降3.6毫米汞柱(范围为0.5 - 10.0毫米汞柱)。这种降低随着年龄增长以及血压较高者而增加。因此,对于最适合高血压非药物治疗的人群——即轻度高血压的年轻患者,钠限制似乎用处有限。