咪达唑仑与麻醉。
Midazolam and anaesthesia.
作者信息
Gemperle M, Kapp W
出版信息
Br J Clin Pharmacol. 1983;16 Suppl 1(Suppl 1):187S-190S. doi: 10.1111/j.1365-2125.1983.tb02293.x.
Abstract
By virtue of its physico-chemical properties and its rapid biotransformation, midazolam is an important addition in certain areas in anaesthesia. Of particular importance are its good local tissue tolerance after intramuscular injection, the absence of venous irritation, and the rapid start of metabolism with good control of action. Midazolam is suitable for both oral and intramuscular administration as premedication in anaesthesia. The compound can also be used for the induction of anaesthesia in combination with analgesics.
摘要
凭借其理化性质和快速生物转化作用，咪达唑仑在麻醉的某些领域是一种重要的添加药物。特别重要的是其肌内注射后良好的局部组织耐受性、无静脉刺激性以及代谢迅速且作用可控。咪达唑仑适用于麻醉前口服和肌内给药。该化合物还可与镇痛药联合用于诱导麻醉。
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2
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Anesthesiology. 1981 Nov;55(5):527-32. doi: 10.1097/00000542-198111000-00008.
3
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Anesthesiology. 1981 Jun;54(6):505-10. doi: 10.1097/00000542-198106000-00010.
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[The effect of midazolam on general hemodynamics and cerebral blood flow in animals and man (author's transl)].
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