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咪达唑仑与麻醉。

Midazolam and anaesthesia.

作者信息

Gemperle M, Kapp W

出版信息

Br J Clin Pharmacol. 1983;16 Suppl 1(Suppl 1):187S-190S. doi: 10.1111/j.1365-2125.1983.tb02293.x.

DOI:10.1111/j.1365-2125.1983.tb02293.x
PMID:6138076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1428109/
Abstract

By virtue of its physico-chemical properties and its rapid biotransformation, midazolam is an important addition in certain areas in anaesthesia. Of particular importance are its good local tissue tolerance after intramuscular injection, the absence of venous irritation, and the rapid start of metabolism with good control of action. Midazolam is suitable for both oral and intramuscular administration as premedication in anaesthesia. The compound can also be used for the induction of anaesthesia in combination with analgesics.

摘要

凭借其理化性质和快速生物转化作用，咪达唑仑在麻醉的某些领域是一种重要的添加药物。特别重要的是其肌内注射后良好的局部组织耐受性、无静脉刺激性以及代谢迅速且作用可控。咪达唑仑适用于麻醉前口服和肌内给药。该化合物还可与镇痛药联合用于诱导麻醉。

相似文献

1
Midazolam and anaesthesia.咪达唑仑与麻醉。
Br J Clin Pharmacol. 1983;16 Suppl 1(Suppl 1):187S-190S. doi: 10.1111/j.1365-2125.1983.tb02293.x.
2
Premedication with intramuscular midazolam: effect on induction time with intravenous midazolam compared to intravenous thiopentone or ketamine.肌肉注射咪达唑仑进行术前用药：与静脉注射硫喷妥钠或氯胺酮相比，对静脉注射咪达唑仑诱导时间的影响。
Can Anaesth Soc J. 1984 Jul;31(4):359-63. doi: 10.1007/BF03015402.
3
Midazolam: pharmacology and uses.咪达唑仑：药理学与用途
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4
Clonidine in paediatric anaesthesia: review of the literature and comparison with benzodiazepines for premedication.可乐定在小儿麻醉中的应用：文献综述及与苯二氮䓬类药物用于术前用药的比较
Acta Anaesthesiol Scand. 2006 Feb;50(2):135-43. doi: 10.1111/j.1399-6576.2006.00940.x.
5
Antidiuretic hormone concentrations following midazolam premedication.咪达唑仑术前用药后的抗利尿激素浓度。
Anaesthesia. 1983 Dec;38(12):1217-20. doi: 10.1111/j.1365-2044.1983.tb12529.x.
6
Sedation for local anaesthesia. Comparison of intravenous midazolam and diazepam.局部麻醉的镇静作用。静脉注射咪达唑仑与地西泮的比较。
Anaesthesia. 1984 Apr;39(4):372-6. doi: 10.1111/j.1365-2044.1984.tb07281.x.
7
[Intramuscular premedication with midazolam in infants and children].
Ann Fr Anesth Reanim. 1984;3(5):346-50. doi: 10.1016/s0750-7658(84)80071-4.
8
Midazolam, a new intravenous induction agent for anaesthesia.咪达唑仑，一种新型静脉麻醉诱导剂。
S Afr Med J. 1982 Feb 20;61(8):274-6.
9
Comparison of midazolam and flunitrazepam for night sedation. A randomised double-blind study.
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10
[Hemodynamic effects of midazolam and flunitrazepam used as induction agents in cardiac patients].
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引用本文的文献

1
[Drugs for intravenous induction of anesthesia: ketamine, midazolam and synopsis of current hypnotics].[静脉麻醉诱导药物：氯胺酮、咪达唑仑及当前催眠药概述]
Anaesthesist. 2018 Aug;67(8):617-634. doi: 10.1007/s00101-018-0469-7.
2
Premedication with midazolam in intellectually disabled dental patients: intramuscular or oral administration? A retrospective study.智力残疾牙科患者使用咪达唑仑进行术前用药：肌肉注射还是口服给药？一项回顾性研究。
Med Oral Patol Oral Cir Bucal. 2016 Jul 1;21(4):e470-6. doi: 10.4317/medoral.21086.
3
New intravenous anaesthetics and neuromuscular blocking drugs. A review of their properties and clinical use.新型静脉麻醉药和神经肌肉阻滞药。其特性及临床应用综述。
Drugs. 1987 Jul;34(1):98-135. doi: 10.2165/00003495-198734010-00004.
4
Effects of an intrathecally administered benzodiazepine receptor agonist, antagonist and inverse agonist on morphine-induced inhibition of a spinal nociceptive reflex.鞘内注射苯二氮䓬受体激动剂、拮抗剂和反向激动剂对吗啡诱导的脊髓伤害性反射抑制的影响。
Br J Pharmacol. 1988 Apr;93(4):964-8. doi: 10.1111/j.1476-5381.1988.tb11486.x.
5
Comparison of the amnesic effects of midazolam and diazepam.
Psychopharmacology (Berl). 1991;103(4):545-50. doi: 10.1007/BF02244257.

本文引用的文献

1
Respiratory depression by midazolam and diazepam.咪达唑仑和地西泮所致的呼吸抑制
Anesthesiology. 1980 Dec;53(6):494-7. doi: 10.1097/00000542-198012000-00010.
2
Sperm studies in anesthesiologists.麻醉医生的精子研究。
Anesthesiology. 1981 Nov;55(5):527-32. doi: 10.1097/00000542-198111000-00008.
3
Reproduction and fetal development in mice chronically exposed to enflurane.长期暴露于恩氟烷的小鼠的生殖与胎儿发育
Anesthesiology. 1981 Jun;54(6):505-10. doi: 10.1097/00000542-198106000-00010.
4
[The effect of midazolam on general hemodynamics and cerebral blood flow in animals and man (author's transl)].
Arzneimittelforschung. 1981;31(12a):2236-7.
5
[Haemodynamic effects and characteristics of midazolam during induction of anesthesia (author's transl)].麻醉诱导期间咪达唑仑的血流动力学效应及特征（作者译）
Arzneimittelforschung. 1981;31(12a):2227-32.
6
Spontaneous breathing with a T-piece circuit: minimum fresh gas/minute volume ratio which prevents rebreathing.使用T形管回路的自主呼吸：防止重复呼吸的最低新鲜气体/分钟通气量比值。
Anesthesiology. 1982 Jun;56(6):449-52.
7
Comparative haemodynamic and respiratory effects of midazolam and flunitrazepam as induction agents in cardiac surgery.
Arzneimittelforschung. 1981;31(12a):2264-7.
8
[Intramuscular application of midazolam. Its effect upon CNS and respiration (author's transl)].
Arzneimittelforschung. 1981;31(12a):2224-5.
9
I.V. midazolam as an induction agent for anaesthesia: a study in volunteers.静脉注射咪达唑仑作为麻醉诱导剂：一项在志愿者中的研究。
Br J Anaesth. 1980 Sep;52(9):907-11. doi: 10.1093/bja/52.9.907.