• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

产肠毒素大肠杆菌的K99表面血凝素可识别血型糖蛋白及其他复合糖缀合物的末端N-乙酰半乳糖胺和唾液酸残基。

K99 surface haemagglutinin of enterotoxigenic E. coli recognize terminal N-acetylgalactosamine and sialic acid residues of glycophorin and other complex glycoconjugates.

作者信息

Lindahl M, Wadström T

出版信息

Vet Microbiol. 1984 Jul;9(3):249-57. doi: 10.1016/0378-1135(84)90042-7.

DOI:10.1016/0378-1135(84)90042-7
PMID:6147916
Abstract

The possible nature of the erythrocyte receptor for K99 haemagglutinin is described. The receptor is a glycophorin which possesses NANA alpha 2-6 GalNAc structures for which this haemagglutinin has a strong affinity. Human, porcine and equine erythrocytes which are haemagglutinated by K99 all have similar glycophorin oligosaccharide structures. K99 has affinity for both NANA and GalNAc at terminal positions, but the affinity for alpha 2-6-linked NANA is higher than for alpha 2-8-linked NANA.

摘要

描述了K99血凝素红细胞受体的可能性质。该受体是一种血型糖蛋白，具有N-乙酰神经氨酸α2-6N-乙酰半乳糖胺结构，这种血凝素对其具有很强的亲和力。被K99凝集的人、猪和马的红细胞都具有相似的血型糖蛋白寡糖结构。K99对末端位置的N-乙酰神经氨酸和N-乙酰半乳糖胺都有亲和力，但对α2-6连接的N-乙酰神经氨酸的亲和力高于对α2-8连接的N-乙酰神经氨酸的亲和力。

相似文献

1
K99 surface haemagglutinin of enterotoxigenic E. coli recognize terminal N-acetylgalactosamine and sialic acid residues of glycophorin and other complex glycoconjugates.产肠毒素大肠杆菌的K99表面血凝素可识别血型糖蛋白及其他复合糖缀合物的末端N-乙酰半乳糖胺和唾液酸残基。
Vet Microbiol. 1984 Jul;9(3):249-57. doi: 10.1016/0378-1135(84)90042-7.
2
Isolation and structural characterization of the equine erythrocyte receptor for enterotoxigenic Escherichia coli K99 fimbrial adhesin.产肠毒素大肠杆菌K99菌毛黏附素的马红细胞受体的分离与结构表征
Infect Immun. 1984 Nov;46(2):578-84. doi: 10.1128/iai.46.2.578-584.1984.
3
Sialic acid and N-acetylgalactosamine specific bacterial lectins of enterotoxigenic Escherichia coli (ETEC).产肠毒素大肠杆菌（ETEC）的唾液酸和N - 乙酰半乳糖胺特异性细菌凝集素。
Adv Exp Med Biol. 1988;228:123-52. doi: 10.1007/978-1-4613-1663-3_6.
4
Immunochemical studies on the differential binding properties of two monoclonal antibodies reacting with Tn red cells.关于两种与Tn红细胞反应的单克隆抗体的差异结合特性的免疫化学研究。
Transfusion. 1991 Feb;31(2):142-9. doi: 10.1046/j.1537-2995.1991.31291142945.x.
5
Monoclonal antibodies against glycophorins.抗血型糖蛋白的单克隆抗体。
Rev Fr Transfus Immunohematol. 1988 Apr;31(2):261-71. doi: 10.1016/s0338-4535(88)80112-0.
6
High-frequency antigens of human erythrocyte membrane sialoglycoproteins. VI. Monoclonal antibodies reacting with the N-terminal domain of glycophorin C.
Biol Chem Hoppe Seyler. 1989 Aug;370(8):849-54. doi: 10.1515/bchm3.1989.370.2.849.
7
Monoclonal antibodies specific for the M- and N-forms of human glycophorin A.对人血型糖蛋白A的M型和N型具有特异性的单克隆抗体。
Mol Immunol. 1983 Dec;20(12):1353-62. doi: 10.1016/0161-5890(83)90166-9.
8
Localization and function of FanH and FanG, minor components of K99 fimbriae of enterotoxigenic Escherichia coli.产肠毒素大肠杆菌K99菌毛次要成分FanH和FanG的定位与功能
Microb Pathog. 1991 Nov;11(5):325-36. doi: 10.1016/0882-4010(91)90018-6.
9
The site of bluetongue virus attachment to glycophorins from a number of animal erythrocytes.蓝舌病毒与多种动物红细胞糖蛋白的附着位点。
J Gen Virol. 1989 Dec;70 ( Pt 12):3347-53. doi: 10.1099/0022-1317-70-12-3347.
10
Evaluation of a monoclonal antibody to the K99 fimbrial adhesin produced by Escherichia coli enterotoxigenic for calves, lambs and piglets.对一种针对产肠毒素大肠杆菌K99菌毛黏附素的单克隆抗体的评估，该大肠杆菌对犊牛、羔羊和仔猪具有致病性。
Res Vet Sci. 1985 Jul;39(1):75-9.

引用本文的文献

1
Supplementation of oligosaccharide-based polymer enhanced growth and disease resistance of weaned pigs by modulating intestinal integrity and systemic immunity.基于寡糖的聚合物补充剂通过调节肠道完整性和全身免疫力来促进断奶仔猪的生长并增强其抗病能力。
J Anim Sci Biotechnol. 2022 Jan 12;13(1):10. doi: 10.1186/s40104-021-00655-2.
2
Binding of milk oligosaccharides by several enterotoxigenic Escherichia coli strains isolated from calves.从犊牛分离出的几种产肠毒素大肠杆菌菌株对乳寡糖的结合作用。
Glycoconj J. 2002 Jan;19(1):5-11. doi: 10.1023/a:1022572628891.
3
Pilus-mediated binding of bovine enterotoxigenic Escherichia coli to calf small intestinal mucins.
菌毛介导的牛产肠毒素大肠杆菌与犊牛小肠黏蛋白的结合
Infect Immun. 1987 May;55(5):1216-23. doi: 10.1128/iai.55.5.1216-1223.1987.
4
Ganglioside epitope recognized by K99 fimbriae from enterotoxigenic Escherichia coli.产肠毒素大肠杆菌K99菌毛识别的神经节苷脂表位
Infect Immun. 1989 Mar;57(3):907-11. doi: 10.1128/iai.57.3.907-911.1989.
5
Glycoprotein glycans that inhibit adhesion of Escherichia coli mediated by K99 fimbriae: treatment of experimental colibacillosis.抑制由K99菌毛介导的大肠杆菌黏附的糖蛋白聚糖：实验性大肠杆菌病的治疗
Infect Immun. 1990 Jan;58(1):98-106. doi: 10.1128/iai.58.1.98-106.1990.
6
Swine and cattle enterotoxigenic Escherichia coli-mediated diarrhea. Development of therapies based on inhibition of bacteria-host interactions.猪和牛产肠毒素大肠杆菌介导的腹泻。基于抑制细菌与宿主相互作用的治疗方法的开发。
Eur J Epidemiol. 1991 Nov;7(6):588-604. doi: 10.1007/BF00218668.