Blumenkrantz N, Asboe-Hansen G
Acta Derm Venereol. 1980;60(2):115-18.
The urinary excretion of uronic acid and the hydroxyproline of a urinary fraction of high molecular weight collagen peptides (% of total Hyp) indicate disease activity in generalized scleroderma. A significant decrease in the content of Hyp and Hyl in the skin of sclerodermal patients is not related to activity, but rather to the duration of the disease. Parallel analyses of skin and urine of the same patients are reported.
尿中糖醛酸的排泄以及高分子量胶原肽尿组分中的羟脯氨酸（占总羟脯氨酸的百分比）可表明系统性硬皮病的疾病活动情况。硬皮病患者皮肤中羟脯氨酸（Hyp）和羟赖氨酸（Hyl）含量的显著降低与疾病活动无关，而与疾病持续时间有关。本文报告了对同一患者的皮肤和尿液进行的平行分析。
