Minckler D S
Arch Ophthalmol. 1980 Sep;98(9):1630-6. doi: 10.1001/archopht.1980.01020040482019.
Horseradish peroxidase was injected into various areas of the optic disc of monkeys to label retrograde axoplasmic transport and permit identification and mapping of ganglion cells projecting through the areas of injection. Peripheral ganglion cell axons project through the deeper layers of the peripapillary nerve fiber layer (NFL) and enter the peripheral optic nerve. Peripapillary ganglion cell axons project through those coming from peripheral locations to superficial positions in the NFL, then to the central optic nerve. The Bjerrum portion of the optic nerve head includes approximately the central 30 degrees of the superior and inferior temporal quadrants of the disc. The course of nerve fiber bundles corresponding to those most susceptible to glaucoma (Bjerrum area) is regularly and predictably organized horizontally and vertically in the nerve head.
将辣根过氧化物酶注射到猴子视盘的各个区域,以标记逆行轴浆运输,并允许识别和绘制通过注射区域投射的神经节细胞。周边神经节细胞轴突穿过乳头周围神经纤维层(NFL)的较深层,进入周边视神经。乳头周围神经节细胞轴突穿过来自周边位置的轴突,到达NFL的浅表位置,然后进入中央视神经。视神经乳头的 Bjerrum 部分大约包括视盘颞上象限和颞下象限的中央 30 度。与最易患青光眼的区域(Bjerrum 区)相对应的神经纤维束在神经乳头中呈水平和垂直方向有规律且可预测地排列。