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二乙氨基二硫代甲酸钠与溶菌酶在对半抗原-载体复合物免疫应答过程中的相互作用。

Interactions between sodium diethyl-dithiocarbamate and lysozyme during the immune response to a hapten-carrier complex.

作者信息

Neveu P J

出版信息

Int Arch Allergy Appl Immunol. 1981;65(1):76-80. doi: 10.1159/000232740.

DOI:10.1159/000232740
PMID:6163738
Abstract

The effects of lysozyme and sodium diethyl-dithiocarbamate (DTC) were studied on antibody synthesis induced by immunization with a hapten-carrier complex. The immunomodulating effects of lysozyme could be partially reversed by DTC, a sulphur derivative which has been previously shown to modulate the immune response, probably at the macrophage level. The mechanisms whereby lysozyme and DTC modulated the immune response are discussed.

摘要

研究了溶菌酶和二乙氨基二硫代甲酸钠（DTC）对由半抗原-载体复合物免疫诱导的抗体合成的影响。溶菌酶的免疫调节作用可被DTC部分逆转，DTC是一种硫衍生物，先前已证明它可能在巨噬细胞水平调节免疫反应。文中讨论了溶菌酶和DTC调节免疫反应的机制。

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