卡介苗对在对半抗原载体复合物早期反应期间细胞免疫和体液免疫的影响。
The effects of BCG on both cellular and humoral immunity during the early response to a hapten carrier complex.
作者信息
Neveu P J
出版信息
Clin Exp Immunol. 1976 Oct;26(1):169-72.
Abstract
Cell-mediated reactions to the carrier and antibody-mediated reactions to hapten and carrier were studied in guinea-pigs treated with a single i.v. injection of BCG at different intervals of time before immunization with two different doses of a hapten-carrier complex. The results clearly show that BCG-induced delayed hypersensitivity reactions to the carrier and decreased antibody synthesis to the hapten. It is proposed that BCG acts on a dispatcher cell which controls both cellular and humoral immunity.
摘要
在用两种不同剂量的半抗原-载体复合物免疫前的不同时间间隔，对豚鼠进行单次静脉注射卡介苗处理，研究了对载体的细胞介导反应以及对半抗原和载体的抗体介导反应。结果清楚地表明，卡介苗诱导了对载体的迟发型超敏反应，并降低了对半抗原的抗体合成。有人提出，卡介苗作用于一个控制细胞免疫和体液免疫的调度细胞。
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The effects of BCG on both cellular and humoral immunity during the early response to a hapten carrier complex.卡介苗对在对半抗原载体复合物早期反应期间细胞免疫和体液免疫的影响。
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引用本文的文献
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Stimulation and inhibition of macrophages prior to immunization with a hapten-carrier conjugate.在用半抗原-载体偶联物免疫之前对巨噬细胞进行刺激和抑制。
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