Oepen G, Doerr M, Thoden U
Electroencephalogr Clin Neurophysiol. 1981 Jun;51(6):666-70. doi: 10.1016/0013-4694(81)90211-x.
In 13 patients suffering from Huntington's chorea (H.Ch.) VEPs and SSEPs were investigated in comparison with 9 clinically unaffected offsprings and 40 normal adults. (1) The mean amplitude of VEPs was reduced in all patients and in 4 out of 9 offsprings. (2) Latencies of P100 in VEPs were normal in all subjects. (3) The late components were reduced in amplitude and rather irregular in shape. (4) The latencies of SSEPs were slightly prolonged, less marked in the early peaks and more pronounced in the later ones. (5) The late components after 70--100 msec were often attenuated or even absent. (6) The mean amplitude of P1/N2 was remarkably reduced. (7) Interhemispheric asymmetries were pronounced in 3 out of 9 offsprings.
对13例患有亨廷顿舞蹈症（H.Ch.）的患者进行了视觉诱发电位（VEPs）和躯体感觉诱发电位（SSEPs）的研究，并与9名临床无症状的后代及40名正常成年人进行了比较。（1）所有患者及9名后代中的4人，其VEPs的平均波幅降低。（2）所有受试者的VEPs中P100的潜伏期正常。（3）晚期成分波幅降低，形状相当不规则。（4）SSEPs的潜伏期略有延长，早期波峰处不太明显，后期波峰处更明显。（5）70 - 100毫秒后的晚期成分常减弱甚至消失。（6）P1/N2的平均波幅显著降低。（7）9名后代中有3人半球间不对称明显。
