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寡制菌素,具有淀粉酶抑制活性的新型抗生素。I. 生产、分离与特性鉴定

Oligostatins, new antibiotics with amylase inhibitory activity. I. Production, isolation and characterization.

作者信息

Itoh J, Omoto S, Shomura T, Ogino H, Iwamatsu K, Inouye S, Hidaka H

出版信息

J Antibiot (Tokyo). 1981 Nov;34(11):1424-8. doi: 10.7164/antibiotics.34.1424.

Abstract

Oligostatins C, D and E, three new antibiotics were found in the culture filtrate of Streptomyces myxogenes nov. sp. SF-1130. Their spectral and chemical properties suggested that oligostatins were basic oligosaccharide antibiotics. They exhibited not only antibacterial activity but also strong amylase inhibitory activity.

摘要

从新的粘链霉菌SF-1130的培养滤液中发现了三种新抗生素——寡制菌素C、D和E。它们的光谱和化学性质表明,寡制菌素是碱性寡糖抗生素。它们不仅具有抗菌活性,还具有很强的淀粉酶抑制活性。

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