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A new aminoglycoside antibiotic, sannamycin C and its 4-N-glycyl derivative.

作者信息

Deushi T, Yamaguchi T, Kamiya K, Iwasaki A, Mizoguchi T, Nakayama M, Watanabe I, Itoh H, Mori T

出版信息

J Antibiot (Tokyo). 1980 Nov;33(11):1274-80. doi: 10.7164/antibiotics.33.1274.

DOI:10.7164/antibiotics.33.1274
PMID:6894748
Abstract

Streptomyces sannanensis KC-7038 used for the production of sannamycins A and B has also produced another antibiotic sannamycin C, in the culture broth. Physico-chemical characterization revealed that sannamycin C is a new aminoglycoside antibiotic having 6-N-methylpurpurosamine C and 2-deoxy-3-epi-fortamine. Its 4-N-glycyl derivative indicated inhibitory activity against Gram-positive and Gram-negative bacteria containing aminoglycoside resistant strains.

摘要

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