Krug H, Kühndel K, Ebeling K
Arch Geschwulstforsch. 1976;46(4):294-303.
1625 cervical smears from 397 women were investigated in special cytological consultations. On the same material 693 impulse cytophotometric (ICP) measurements were made, stained with ethidium bromide after pepsination. In 207 patients the diagnosis was certain by histology. The mean height of the 4c-peak (in 0/00 of the 2c-peak) raises with the Papanicolaou grading from 38,2 in Pap. I up to 128,8 in Pap. V. In histological confirmed cases in dysplasia the mean 4c-height was 79,5 and in carcinoma 102.2. If only one ICP investigation was turned to account there are some disagreements between the ICP value and the diagnosis finally resulting from the clinical and cytological course. The differences are considerably diminished by repeated ICP investigations. Therefore ICP measurements are a valuable aid in interpreting cytodiagnostic problems. They often facilitate the choice of further diagnostic and therapeutic procedures.
在特殊细胞学会诊中，对397名女性的1625份宫颈涂片进行了研究。对相同材料进行了693次脉冲细胞光度测定（ICP），在胃蛋白酶消化后用溴化乙锭染色。207例患者的诊断经组织学确定。4c峰的平均高度（以2c峰的百分比表示）随着巴氏分级从巴氏I级的38.2升高至巴氏V级的128.8。在组织学确诊的发育异常病例中，4c平均高度为79.5，在癌病例中为102.2。如果仅考虑一次ICP检查，ICP值与最终根据临床和细胞学过程得出的诊断之间存在一些分歧。通过重复ICP检查，差异会大大减小。因此，ICP测量在解释细胞诊断问题方面是一种有价值的辅助手段。它们常常有助于选择进一步的诊断和治疗程序。
