干扰素诱导的单核细胞膜变化：视黄醇和视黄酸的抑制作用。
Interferon-induced changes in the monocyte membrane: inhibition by retinol and retinoic acid.
作者信息
Rhodes J, Stokes P
出版信息
Immunology. 1982 Mar;45(3):531-6.
Abstract
The effects of human interferon-beta on human peripheral blood monocyte function were examined in vitro. Interferon-beta was shown to increase substantially the expression of both Fc gamma receptors and HLA-DR antigens defined by monoclonal antibody. Retinol and retinoic acid were found to be antagonistic to these effects of interferon and physiological concentrations were sufficient to inhibit changes in the monocyte membrane induced by relatively high concentrations of interferon.
摘要
在体外研究了人β干扰素对人外周血单核细胞功能的影响。结果显示，β干扰素可显著增加由单克隆抗体所界定的Fcγ受体和HLA - DR抗原的表达。发现视黄醇和视黄酸对干扰素的这些作用具有拮抗作用，生理浓度的视黄醇和视黄酸足以抑制相对高浓度干扰素诱导的单核细胞膜变化。
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本文引用的文献
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